WHOLE GENOME RESEQUENCING REVEALS NATURAL TARGET SITE PREFERENCES OF TRANSPOSABLE ELEMENTS IN DROSOPHILA MELANOGASTER.

Whole genome resequencing reveals natural target site preferences of transposable elements in Drosophila melanogaster.

Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity.While the target site preferences of some engineered transposable elements are well studied, the natural target preferences of most transposable elements Front Loader are poorly characterized.Using

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Outer Membrane Protein A Conservation among Orientia tsutsugamushi Isolates Suggests Its Potential as a Protective Antigen and Diagnostic Target

Scrub typhus threatens one billion people in the Asia-Pacific area and cases have emerged outside this region.It is caused by infection with any of the multitude of strains of the bacterium Orientia tsutsugamushi.A vaccine that affords heterologous protection and a commercially-available molecular diagnostic assay are lacking.Herein, we determined

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Physical Activity Induces Nucleus Accumbens Genes Expression Changes Preventing Chronic Pain Susceptibility Promoted by High-Fat Diet and Sedentary Behavior in Mice

Recent findings from rodent studies suggest that high-fat diet (HFD) increases hyperalgesia independent of obesity status.Furthermore, weight loss interventions such as voluntary physical activity (PA) for adults with obesity or overweight was reported to promote pain reduction in humans with chronic pain.However, regardless of obesity status, it i

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